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Degradability of sponges in the presence or absence of matrix metalloproteinase (MMP)-2 and -9. (A) Degradability of sponges in phosphate-buffered saline (PBS). (B) Degradation of sponges in working solution with activated MMP-2 or -9. Degradation of sponges was measured using BCA protein assays. The sponges were immersed in PBS or working solution for up to 1 week. Data are the means and SDs. ** p < 0.01 (n = 3, ANOVA with Tukey-Kramer tests).
