Table 4:
Age-matched prevalence estimates of drusen and epiretinal membrane in this study (overall and in the multiple sclerosis subgroup) compared to population-based estimates obtained from the Beaver Dam Eye Study
| Age, yrs | Drusen prevalence, % (No. at Risk; 95% CI)1 | ERM prevalence, % (No. at Risk; 95% CI)2 | ||||
|---|---|---|---|---|---|---|
| Overall cohort | MS subgroup | Population-based estimates | Overall cohort | MS subgroup | Population-based estimates2 | |
| <43 | 3.2 (665; 2.1–4.8) | 2.7 (407; 1.5–4.8) | - (0) | 1.4 (665; 0.7–2.6) | 1.0 (407; 0.4–2.6) | - (0) |
| 43–54 | 7.4 (488; 5.4–10.1) | 6.5 (262; 4.1–10.2) | 7.1 (1504; 5.9–8.5) | 4.3 (488; 2.8–6.5) * | 5.0 (262; 2.9–8.4) * | 1.7 (1419; 1.1–2.5) |
| 55–64 | 8.6 (221; 5.5–13.1) ǂ | 8.1 (124; 4.4–14.5) | 16.3 (1301; 14.3–18.4) | 11.8 (221; 8.1–16.8) | 12.9 (124; 8.0–20.1) | 6.7 (1145; 5.3–8.3) |
| 65–74 | 10.6 (66; 5.0–21.0) ǂ | 15 (20; 4.4–40.4) | 23.9 (1249; 21.6–26.4) | 30.3 (66; 20.2–42.7) * | 35 (20; 16.4–59.6) * | 11.7 (1035; 9.8–13.8) |
| 75+ | 80 (5; 0.1–99.2) | - (0) | 44.3 (713; 40.6–48.1) | 60 (5; 8.1–96.2) | - (0) | 8.5 (526; 6.3–11.3) |
1
Population-based estimate data extracted from Klein et al15.
2
Population-based estimate data obtained by weighted-averaging of the ERM prevalence estimates of both genders in each age stratum of the right eyes included in the Beaver Dam Eye study16.
*
Denotes a significantly higher prevalence rate compared to general population estimates.
ǂ
Denotes a significantly lower prevalence rate compared to general population estimates.
Abbreviations: CI = confidence interval; ERM = epiretinal membrane; MS = multiple sclerosis.