. 2019 Dec 11;28(1):44–50. doi: 10.4103/ipj.ipj_57_19

Table 4.

Score of baclofen and topiramate group in obsessive and compulsive drinking scale during each assessment

Variables	Group	Baseline	1^st week	2^nd week	3^rd week	4^th week
Dose (mg) (mention values as mean±SD)	Baclofen	-	20±0.0	23.04±6.641	23.91±6.593	23.81±6.890
Dose (mg) (mention values as mean±SD)	Topiramate	-	25±0.0	50±0.0	120±25.162	125±35.355
OCD (O)	Baclofen	13.24±2.654	9.96±3.994^@	6.64±4.156^∞	3.52±4.155^€	1.19±3.501^©
OCD (O)	Topiramate	14.0±3.628	13.04±3.702*	10.08±4.319*^,∞	8.27±4.783*^,€	4.05±4.892*^,©
OCD (C)	Baclofen	13.28±2.913	7.76±5.789^@	2.56±5.007^∞	1.95±4.324^€	0.81±3.709^©
OCD (C)	Topiramate	14.36±3.321	13.04±3.948*	9.36±5.724**^,∞	6.52±6.816**^,€	2.77±5.275*^,©
OCD (T)	Baclofen	26.52±5.581	16.64±10.123^@	9.21±7.942^∞	5.48±7.983^€	2.0±7.036^©
OCD (T)	Topiramate	28.36±6.769	26.08±7.410*	19.44±9.747**^,∞	14.5±11.359**^,€	6.83±9.855*^,©
VAS	Baclofen	81.2±8.817	63.2±17.072^@	39.56±14.924^∞	24.78±23.906^€	6.19±18.568^©
VAS	Topiramate	82.4±10.116	78±11.547*	65.2±17.823*^,∞	48.63±26.603*^,€	25.56±28.122*^,©
Average drinking days/past week	Baclofen	6.72±0.791	2.36±2.721^@	0.782±1.730^∞	0.434±1.502^€	0.428±1.535^©
Average drinking days/past week	Topiramate	6.44±1.044	5.12±1.833*	3.32±2.495^∞	2.22±2.810^€	1.00±2.143^©
Average number of drinks	Baclofen	10.16±0.862	4.10±2.030^@	2.356±1.466^∞	1.356±1.160^€	0.871±1.434^©
Average number of drinks	Topiramate	11.92±0.959	6.40±0.931*	4.96±1.262^∞	3.045±1.565^€	1.471±1.395^©

*Significant difference between baclofen and topiramate (0.05), **Significant difference between baclofen and topiramate (0.001), ^@Significant difference between baseline and 1^st week assessment, ^∞Significant difference between baseline and 2^nd week assessment, ^€Significant difference between baseline and 3^rd week assessment, ^©Significant difference between baseline and 4^th week assessment. OCD – Obsessive and compulsive drinking; SD – Standard deviation; VAS – Visual Analog Scale