Table 1. Univariate analysis of risk factors associated with H. pylori.

AZA, azathioprine; CD, Crohn’s disease; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; 5-ASA, 5-aminosalicylic acid; 6-MP, 6-mercaptopurine

*H.pylori positive (12) were tested for C. difficile; H.pylori negative (56) were tested for C. difficile.

Variable	H. pylori positive (n = 19)	H. pylori negative (n = 72)	P-value
Mean age, years	46.5 ± 3.4	47.0  ± 1.8	0.896
Male sex	5 (26.3%)	22 (30.6%)	0.786
Age at CD diagnosis	32.3 ± 2.9	33.7  ± 1.7	0.709
Disease extension
Ileal	2 (10.5%)	8 (11.1%)	0.555
Ileocolonic	9 (47.3%)	44 (61.1%)
Colonic	8 (42.2%)	20 (27.8%)
Diarrhea on CD diagnosis	15 (78.9%)	48 (66.7%)	0.406
Bleeding on CD diagnosis	5 (26.3%)	18 (25.0%)	0.560
Abdominal pain on CD diagnosis	17 (89.5%)	52 (72.2%)	0.147
History of C. difficile infection*	2 (17.6%)	10 (17.9%)	0.645
Arthritis	2 (10.5%)	12 (16.7%)	0.726
Fistulizing/stricturing disease	4 (21.1%)	40 (55.6%)	0.009
Active colitis on random biopsies	8 (42.1%)	54 (77.1%)	0.005
Use of 5-ASA	12 (63.2%)	51 (70.8%)	0.580
Use of 6-MP/AZA	5 (26.3%)	21 (29.2%)	1.000
Use of methotrexate	1  (5.6%)	03 (4.3%)	1.000
Use of steroids	14 (73.7%)	64 (88.9%)	0.135
Use of any biologic	7 (36.8%)	37 (51.4%)	0.309
CRP	5.7 ± 1.8	23.7 ± 5.3	0.112
ESR	25.0 ± 4.1	41.1 ± 4.3	0.053
Fecal Calprotectin	187.5 ± 41.7	159.8 ± 42.5	0.727