Table 4.

The average NMIs, ACCs and ARIs and standard errors obtained by the ISC and other comparison partners on colorectal cancer datasets

	Methods	DNA methylation+	DNA methylation+	miRNA expression+	DNA methylation+miRNA
		miRNA expression	mRNA expression	mRNA expression	expression+mRNA expression
NMI	SNF	0.247 ±0.001	0.247 ±0.004	0.330 ±0.003	0.276 ±0.000
	Coreg	0.023 ±0.000	0.186 ±0.000	0.186 ±0.000	0.234 ±0.008
	ECMC	0.164 ±0.000	0.164 ±0.000	0.091 ±0.004	0.138 ±0.006
	ISC-C	0.372 ±0.006	0.149 ±0.001	0.137 ±0.015	0.012 ±0.004
	ISC-S1	0.118 ±0.005	0.338 ±0.004	——	0.288 ±0.002
	ISC-S2	0.019 ±0.002	——	0.046 ±0.007	0.009 ±0.005
	ISC-S3	——	0.175 ±0.002	0.263 ±0.003	0.178 ±0.001
ACC	SNF	0.835 ±0.004	0.800 ±0.006	0.847 ±0.003	0.835 ±0.005
	Coreg	0.812 ±0.000	0.812 ±0.000	0.812 ±0.000	0.812 ±0.000
	ECMC	0.741 ±0.000	0.741 ±0.000	0.642 ±0.005	0.706 ±0.004
	ISC-C	0.871 ±0.003	0.602 ±0.002	0.689 ±0.000	0.567 ±0.004
	ISC-S1	0.698 ±0.004	0.859 ±0.004	——	0.843 ±0.006
	ISC-S2	0.583 ±0.009	——	0.685 ±0.008	0.566 ±0.002
	ISC-S3	——	0.779 ±0.007	0.828 ±0.001	0.757 ±0.003
ARI	SNF	0.391 ±0.003	0.310 ±0.005	0.442 ±0.004	0.402 ±0.004
	Coreg	0.031 ±0.003	0.250 ±0.000	0.250 ±0.000	0.336 ±0.013
	ECMC	0.209 ±0.000	0.209 ±0.000	0.080 ±0.005	0.160 ±0.006
	ISC-C	0.506 ±0.001	-0.007 ±0.009	0.113 ±0.003	0.000 ±0.017
	ISC-S1	0.139 ±0.000	0.469 ±0.006	——	0.422 ±0.005
	ISC-S2	0.015 ±0.002	——	0.098 ±0.008	0.011 ±0.009
	ISC-S3	——	0.238 ±0.005	0.384 ±0.006	0.237 ±0.006

The highest NMIs, ACCs and ARIs are marked in bold