Table 4.

The number of pathogenic mutations identified in 253 unpaired tumour samples in five genes that are frequently mutated in ovarian cancer. The number of unique mutations is shown and in brackets the number of samples with at least one mutation is shown

	BRCA1	BRCA2	KRAS	PIK3CA	TP53
MuTect2	1190 (n = 243)	390 (n = 248)	56 (n = 202)	47 (n = 186)	820 (n = 246)
TVC	164 (n = 89)	54 (n = 42)	11 (n = 34)	18 (n = 27)	215 (n = 175)
Common	163 (n = 85)	52 (n = 42)	11 (n = 34)	14 (n = 24)	210 (n = 173)
Common (%)	13.7% (34.4%)	13.3% (16.9%)	19.6% (16.8%)	27.5% (12.7%)	25.5% (69.8%)