Table 4.
Summary of pooled estimates from fitting GLM and GLMM to bootstrap samples from Pancreas dataset
| Fixed effect model - Pancreas | |||||
|---|---|---|---|---|---|
| Estimate | std.error | Statistic | df | p.value | |
| (Intercept) | 4.68 | 0.09 | 52.09 | 9.84 | 0.00 |
| Beta | -0.94 | 0.16 | -5.87 | 4.10 | 0.00 |
| Ductal | -1.14 | 0.14 | -7.91 | 5.87 | 0.00 |
| T2D | 0.06 | 0.12 | 0.51 | 10.22 | 0.62 |
| patientHP1504101_T2D | -0.28 | 0.14 | -2.05 | 7.41 | 0.06 |
| patientHP1504901 | -0.27 | 0.11 | -2.38 | 12.35 | 0.03 |
| patientHP1506401 | -0.39 | 0.12 | -3.34 | 12.35 | 0.01 |
| patientHP1507101 | -0.03 | 0.11 | -0.32 | 12.35 | 0.76 |
| patientHP1508501_T2D | 0.01 | 0.10 | 0.10 | 12.35 | 0.92 |
| patientHP1509101 | -0.87 | 0.14 | -6.42 | 12.35 | 0.00 |
| patientHP1525301_T2D | 0.07 | 0.10 | 0.77 | 12.35 | 0.45 |
| beta:T2D | -0.52 | 0.22 | -2.40 | 5.41 | 0.03 |
| ductal:T2D | 0.59 | 0.19 | 3.12 | 5.54 | 0.01 |
| Mixed effect model - Pancreas | |||||
| Estimate | std.error | Statistic | df | p.value | |
| (Intercept) | 4.37 | 0.12 | 36.20 | 16.21 | 0.00 |
| Beta | -0.94 | 0.16 | -5.87 | 5.99 | 0.00 |
| Ductal | -1.14 | 0.14 | -7.91 | 8.59 | 0.00 |
| T2D | 0.31 | 0.17 | 1.80 | 16.90 | 0.09 |
| beta:T2D | -0.52 | 0.22 | -2.40 | 7.92 | 0.03 |
| ductal:T2D | 0.59 | 0.19 | 3.12 | 8.14 | 0.01 |
Beta, ductal are the cell-type effect. T2D is abbreviation of type two diabetes effect. Subject ID followed by underscore of T2D represents type two diabetes subject. Subject ID without underscore of T2D represents normal subject