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. 2019 Dec 24;20(Suppl 25):700. doi: 10.1186/s12859-019-3275-6

Table 6.

Comparison of the Se, Sp, ACC and MCC between four traditional models and sequence information model on Dataset 2

Membrane protein types Index AAC DipC TipC PseAAC Our model
Se 0.6571 0.5306 0.3388 0.6898 0.8408
Type I Sp 0.9384 0.9643 0.9824 0.9440 0.9806
ACC 0.9193 0.9348 0.9387 0.9267 0.9711
MCC 0.4951 0.4903 0.4156 0.5341 0.7841
Se 0.1139 0.0 0.0 0.0633 0.7468
Type II Sp 0.9901 1.0 1.0 0.9889 0.9739
ACC 0.9709 0.9781 0.9781 0.9686 0.9689
MCC 0.1387 0.0 0.0 0.0696 0.5267
Se 0.0 0.0 0.0 0.0 0.0
Type III Sp 1.0 1.0 1.0 1.0 1.0
ACC 0.9975 0.9975 0.9975 0.9975 0.9975
MCC 0.0 0.0 0.0 0.0 0.0
Se 0.0 0.0 0.0 0.0 0.7647
Type IV Sp 1.0 1.0 1.0 1.0 0.9958
ACC 0.9953 0.9953 0.9953 0.9953 0.9947
MCC 0.0 0.0 0.0 0.0 0.5935
Se 0.8721 0.9290 0.9617 0.8709 0.9157
Mutipass Sp 0.8526 0.7105 0.4885 0.8588 0.9813
ACC 0.8660 0.8607 0.8138 0.8671 0.9362
MCC 0.7022 0.6669 0.5442 0.7058 0.8638
Se 0.0556 0.0 0.0 0.0278 0.0
Lipid-chain-anchored Sp 1.0 1.0 1.0 1.0 0.9983
ACC 0.9906 0.9900 0.9900 0.9903 0.9883
MCC 0.2346 0.0 0.0 0.1659 -0.0041
Se 0.3659 0.0488 0.0 0.3659 0.9024
GPI-anchored Sp 0.9986 1.0 1.0 0.9941 0.9938
ACC 0.9914 0.9892 0.9886 0.9870 0.9928
MCC 0.5203 0.2197 0.0 0.3839 0.7490
Se 0.7425 0.6881 0.5451 0.7797 0.9013
Peripheral Sp 0.8885 0.9164 0.9580 0.8954 0.9418
ACC 0.8602 0.8721 0.8779 0.8729 0.9340
MCC 0.5893 0.5965 0.5740 0.6290 0.8025

Note: Best performing method in bold.