Supplementary Table 3.
Analysis results for 70 SNPs related to CD.
| SNP | Chr. | Gene | Frequency among the CD group | Frequency among controls | Allelic test P-value | OR | 95% CI |
|---|---|---|---|---|---|---|---|
| rs10114470 | 9 | TNFSF15 | 0.3834 | 0.5656 | 1.41E-11 | 0.4774 | (0.3847, 0.5925) |
| rs3810936 | 9 | TNFSF15 | 0.3826 | 0.565 | 2.40E-11 | 0.4772 | (0.3835, 0.5938) |
| rs6478109 | 9 | TNFSF15 | 0.3702 | 0.5386 | 3.55E-10 | 0.5035 | (0.4058, 0.6247) |
| rs6478108 | 9 | TNFSF15 | 0.374 | 0.5425 | 3.71E-10 | 0.5039 | (0.4061, 0.6252) |
| rs4263839 | 9 | TNFSF15 | 0.3729 | 0.5405 | 5.08E-10 | 0.5055 | (0.4072, 0.6277) |
| rs7848647 | 9 | TNFSF15 | 0.3714 | 0.5388 | 5.11E-10 | 0.5059 | (0.4075, 0.628) |
| rs4246905 | 9 | TNFSF15 | 0.2645 | 0.4189 | 1.18E-09 | 0.4989 | (0.3981, 0.6252) |
| rs4574921 | 9 | TNFSF15 | 0.2656 | 0.4189 | 1.55E-09 | 0.5015 | (0.4003, 0.6285) |
| rs6478106 | 9 | TNFSF15 | 0.3249 | 0.1827 | 4.29E-09 | 2.153 | (1.661, 2.79) |
| rs11209032 | 1 | IL-23R | 0.4451 | 0.5598 | 2.35E-05 | 0.6307 | (0.5091, 0.7814) |
| rs6588248 | 1 | IL23R | 0.3119 | 0.4066 | 0.0002632 | 0.6613 | (0.5293, 0.8263) |
| rs7329174 | 13 | ELF1 | 0.2758 | 0.1988 | 0.001074 | 1.535 | (1.186, 1.986) |
| rs422951 | 6 | NOTCH4 | 0.146 | 0.2115 | 0.00125 | 0.6374 | (0.4843, 0.8391) |
| rs7517847 | 1 | IL23R | 0.3831 | 0.4692 | 0.001257 | 0.7025 | (0.5667, 0.871) |
| rs13361189 | 5 | IRGM | 0.5031 | 0.4205 | 0.0024 | 1.395 | (1.125, 1.73) |
| rs10065172 | 5 | IRGM | 0.5 | 0.4186 | 0.002739 | 1.389 | (1.12, 1.722) |
| rs11235604 | 11 | ATG16L2 | 0.1374 | 0.08687 | 0.004163 | 1.674 | (1.173, 2.388) |
| rs888208 | 10 | NKX2–3 | 0.3776 | 0.4537 | 0.004294 | 0.7304 | (0.5886, 0.9064) |
| rs1487630 | 4 | 4p14 | 0.2789 | 0.2115 | 0.004379 | 1.442 | (1.12, 1.855) |
| rs4958847 | 5 | IRGM | 0.3459 | 0.4187 | 0.006374 | 0.7342 | (0.5879, 0.917) |
| rs9637876 | 5 | IRGM | 0.4918 | 0.4189 | 0.007165 | 1.342 | (1.083, 1.664) |
| rs11235667 | 11 | ATG16L2-FCHSD2 | 0.1381 | 0.09073 | 0.007553 | 1.606 | (1.132, 2.278) |
| rs11741861 | 5 | ZNF300 | 0.4706 | 0.4 | 0.00879 | 1.333 | (1.075, 1.654) |
| rs1004819 | 1 | IL23R | 0.3842 | 0.4514 | 0.01217 | 0.7584 | (0.6109, 0.9416) |
| rs10883365 | 10 | LINC01475 | 0.5228 | 0.4554 | 0.01347 | 1.31 | (1.057, 1.623) |
| rs3745635 | 19 | FUT3 | 0.1701 | 0.1236 | 0.01765 | 1.454 | (1.066, 1.982) |
| rs1799987 | 3 | CCR5 | 0.3499 | 0.4115 | 0.01857 | 0.7696 | (0.6187, 0.9573) |
| rs11195128 | 10 | SMNDC1-DUSP5 | 0.1724 | 0.1269 | 0.02095 | 1.433 | (1.055, 1.947) |
| rs514000 | 18 | PTPN2 | 0.4168 | 0.3546 | 0.02101 | 1.301 | (1.04, 1.627) |
| rs4409764 | 10 | NKX2–3 | 0.4765 | 0.5388 | 0.02207 | 0.7792 | (0.6292, 0.9649) |
| rs10947261 | 6 | BTNL2 | 0.335 | 0.281 | 0.03279 | 1.289 | (1.021, 1.628) |
| rs3749172 | 2 | GPR35 | 0.3641 | 0.3105 | 0.04015 | 1.271 | (1.011, 1.599) |
| rs153109 | 16 | IL27 | 0.4074 | 0.3533 | 0.04123 | 1.259 | (1.009, 1.57) |
| rs7765379 | 6 | MHC | 0.1068 | 0.07529 | 0.04907 | 1.469 | (0.9997, 2.159) |
| rs3181374 | 10 | TNFSF8 | 0.425 | 0.4764 | 0.06347 | 0.8124 | (0.6523, 1.012) |
| rs3181036 | 3 | CCR5 | 0.168 | 0.2066 | 0.0651 | 0.7757 | (0.592, 1.016) |
| rs1053004 | 17 | STAT3 | 0.3476 | 0.3923 | 0.08707 | 0.8255 | (0.6626, 1.028) |
| rs6908425 | 6 | CDKAL1 | 0.1476 | 0.1815 | 0.0897 | 0.7811 | (0.587, 1.039) |
| rs7865494 | 9 | TNFSF15 | 0.2879 | 0.249 | 0.109 | 1.219 | (0.9566, 1.554) |
| rs7574865 | 2 | STAT4 | 0.3398 | 0.3813 | 0.1108 | 0.835 | (0.669, 1.042) |
| rs13003464 | 2 | PUS10 | 0.05215 | 0.03475 | 0.1269 | 1.528 | (0.8833, 2.644) |
| rs2004640 | 7 | IRF5 | 0.2945 | 0.2577 | 0.1319 | 1.202 | (0.9459, 1.528) |
| rs7282490 | 21 | LOC105377139 | 0.449 | 0.4884 | 0.1463 | 0.8536 | (0.6894, 1.057) |
| rs1250546 | 10 | ZMIZ1 | 0.4213 | 0.4593 | 0.16 | 0.8571 | (0.6912, 1.063) |
| rs1292053 | 17 | TUBD1 | 0.4483 | 0.4826 | 0.2055 | 0.8712 | (0.7038, 1.079) |
| rs10761659 | 10 | LOC105370520 | 0.2162 | 0.2442 | 0.2187 | 0.8537 | (0.6635, 1.099) |
| rs7608910 | 2 | PUS10 | 0.05263 | 0.03846 | 0.22 | 1.389 | (0.82, 2.353) |
| rs2273650 | 14 | NFKBIA | 0.2684 | 0.2934 | 0.3062 | 0.8835 | (0.6968, 1.12) |
| rs11894081 | 2 | SOX11 | 0.4214 | 0.3944 | 0.3205 | 1.118 | (0.897, 1.394) |
| rs1250569 | 10 | ZMIZ1 | 0.4287 | 0.4535 | 0.3584 | 0.9044 | (0.7298, 1.121) |
| rs2823256 | 21 | LOC101927745 | 0.3126 | 0.3359 | 0.3598 | 0.8992 | (0.7162, 1.129) |
| rs2241880 | 2 | ATG16L1 | 0.3742 | 0.3514 | 0.3813 | 1.104 | (0.8845, 1.378) |
| rs3807306 | 7 | IRF5 | 0.1829 | 0.166 | 0.4147 | 1.125 | (0.848, 1.491) |
| rs72553867 | 5 | IRGM | 0.1596 | 0.1757 | 0.4237 | 0.8908 | (0.671, 1.183) |
| rs7702331 | 5 | LOC105379031 | 0.1154 | 0.1293 | 0.431 | 0.878 | (0.635, 1.214) |
| rs1134986 | 3 | DLG1 | 0.06302 | 0.05405 | 0.4878 | 1.177 | (0.7425, 1.866) |
| rs1801133 | 1 | MTHFR | 0.2957 | 0.2791 | 0.5012 | 1.085 | (0.8561, 1.374) |
| rs3894326 | 19 | FUT3 | 0.1447 | 0.1564 | 0.5467 | 0.913 | (0.6791, 1.228) |
| rs2107538 | 17 | CCL5 | 0.3418 | 0.3295 | 0.6314 | 1.057 | (0.8432, 1.325) |
| rs1799964 | 6 | LTA | 0.1752 | 0.1846 | 0.6486 | 0.9379 | (0.7117, 1.236) |
| rs1800630 | 6 | LTA | 0.1586 | 0.1673 | 0.6617 | 0.938 | (0.7043, 1.249) |
| rs2149085 | 6 | RNASET2 | 0.3929 | 0.3833 | 0.7181 | 1.041 | (0.8362, 1.296) |
| rs1047266 | 8 | TNFRSF10B | 0.277 | 0.2857 | 0.7208 | 0.9577 | (0.7555, 1.214) |
| rs3731772 | 2 | AOX1 | 0.3508 | 0.3417 | 0.7247 | 1.041 | (0.8319, 1.303) |
| rs4462937 | 3 | DNAH12 | 0.3931 | 0.4023 | 0.7281 | 0.962 | (0.7735, 1.197) |
| rs1819333 | 6 | LOC105379031 | 0.3909 | 0.3822 | 0.7426 | 1.037 | (0.8333, 1.292) |
| rs1127354 | 20 | ITPA | 0.1711 | 0.1647 | 0.7537 | 1.047 | (0.7862, 1.394) |
| rs3208181 | 6 | HLA-DQA2 | 0.1245 | 0.1192 | 0.7671 | 1.05 | (0.7585, 1.455) |
| rs1695 | 11 | GSTP1 | 0.1765 | 0.1712 | 0.7941 | 1.038 | (0.7837, 1.375) |
| rs3765534 | 13 | ABCC4 | 0.05183 | 0.05385 | 0.8676 | 0.9605 | (0.5981, 1.543) |
SNPs are ordered according to P values. Chr – chromosome.