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. 2019 Dec 17;25:9637–9650. doi: 10.12659/MSM.917244

Supplementary Table 4.

Analysis results for SNPs related to pCD.

Name Chr. No. Gene or locus Major/minor allele Risk allele Case RAF Control RAF OR (95% CI) P value allele P value genotype
rs72553867 chr5 IRGM C/A A 0.194 0.125 1.685 (1.188–2.390) 0.003 0.002a
rs4958847 chr5 IRGM A/G A 0.688 0.617 1.365 (1.047–1.778) 0.021 0.025c
rs4409764 chr10 NKX2–3 G/T T 0.558 0.487 1.329 (1.033–1.709) 0.027 0.007a
rs888208 chr10 NKX2–3 A/G A 0.656 0.588 1.338 (1.032–1.735) 0.028 0.004a
rs3731772 chr2 AOX1 T/C T 0.681 0.615 1.335 (1.025–1.740) 0.032 0.032a
rs1292053 chr17 TUBD1 G/A A 0.482 0.417 1.300 (1.010–1.674) 0.041 0.035c
rs3894326 chr19 FUT3 A/T A 0.880 0.836 1.438 (1.001–2.064) 0.049 0.045c
rs10883365 chr10 NKX2–3 A/G G 0.548 0.496 1.234 (0.957–1.590) 0.105 0.033a
rs3181374 chr9 TNFSF8 A/G A 0.687 0.642 1.226 (0.939–1.600) 0.135 0.069a
rs11235667 chr11 ATG16L2-FCHSD2 A/G A 0.877 0.844 1.314 (0.914–1.887) 0.139 0.148c
rs3749172 chr2 GPR35 C/A A 0.387 0.343 1.209 (0.926–1.577) 0.162 0.055b
rs2241880 chr2 ATG16L1 A/G G 0.394 0.355 1.185 (0.915–1.534) 0.199 0.182b
rs153109 chr16 IL27 T/C T 0.613 0.573 1.181 (0.914–1.526) 0.204 0.094a
rs1800630 chr6 TNF C/A C 0.857 0.828 1.242 (0.881–1.752) 0.216 0.168b
rs11235604 chr11 ATG16L2 C/T C 0.875 0.848 1.256 (0.873–1.805) 0.219 0.225c
rs7282490 chr21 ICOSLG G/A A 0.468 0.429 1.168 (0.907–1.504) 0.228 0.205b
rs2107538 chr17 CCL5 C/T T 0.360 0.325 1.168 (0.897–1.522) 0.249 0.239c
rs10114470 chr9 TNFSF15 C/T C 0.633 0.598 1.160 (0.897–1.500) 0.259 0.128a
rs514000 chr18 PTPN2 T/C T 0.600 0.564 1.160 (0.895–1.501) 0.262 0.106a
rs11209032 chr1 IL23R-IL12RB2 A/G G 0.464 0.429 1.149 (0.893–1.478) 0.281 0.275a

SNPs are ordered according to P values.

a

p value for the dominant model;

b

p value for the regressive model;

c

p value for the additive model.

Chr – chromosome; RAF – risk allele frequency