Figure 8.

UV-B-induced pigmentation. The dorsal skin of HRM2 mice (A) or brownish guinea pigs (B) was irradiated with UV-B and treated topically with BPT as shown in Figure S1D-E. (A) Photograph of skin pigmentation in HRM2 mice (left). The change of lightening index (△L) in UV-B-exposed skin (right). Data are mean ± SEM. *P < 0.05 vs. UV-B plus vehicle alone. (B) Photograph of skin pigmentation in brownish guinea pigs (upper). UV-B-exposed skin that was stained with Fontana-Masson silver nitrite (lower).