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. 2020 Jan 1;10(1):300–311. doi: 10.7150/thno.38736

Figure 3.

Figure 3

Transduced HepLL and Caki-1 cells co-cultured in the tumor progression model based on metastasis-on-a-chip. (A) Transduction diagram demonstrating the introduction of Green fluorescent protein (GFP) and Red fluorescent protein (RFP). (B) 2D transduction results of HepLL expressing GFP and (C) Caki-1 cells expressing RFP. (D) Confocal images of HepLL and Caki-1 cells co-culture on the tumor progression model based on metastasis-on-a-chip on day 1 and day 7. The ratio of green (E) and red (F) fluorescence expressed on day 7 compared to day 1 (Avg. ± SD, n = 3).