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. 2020 Jan 1;10(1):281–299. doi: 10.7150/thno.35568

Figure 8.

Figure 8

A. The mechanism of CRISPR-Cas9 technology for gene editing. B. CRISPR-Cas 9 nanotherapeutics for cell engineering and the applications in cancer immunotherapy. The CRISPR-Cas 9 system (sgRNA with Cas9 mRNA or DNA or protein) was transported to tumor or immune cells by nanocarriers.