Table 1.
Characteristics of the Study Subjects
| COPD (n = 164) | Non-COPD (n = 22) | p-Value | |
|---|---|---|---|
| Age (years) | 72.2 ± 8.1 | 70.6 ± 9.3 | N.S. |
| Sex (male/female) | 152/12 | 21/1 | |
| BMI (kg/m2) | 23.2 ± 3.2 | 22.6 ± 2.3 | N.S. |
| Smoking history | |||
| Current/former/never† | 33/129/2 | 4/18/0 | |
| Pack-years | 59.6 ± 30.1 | 58.3 ± 38.6 | N.S. |
| mMRC score | 1.2 ± 1.1 | 0.9 ± 1.0 | N.S. |
| Total CAT score | 10.5 ± 7.3 | 10.0 ± 8.0 | N.S. |
| Pulmonary function tests | |||
| VC (L)¶ | 3.5 ± 0.8 | 3.3 ± 0.7 | N.S. |
| FEV1 (L)¶ | 1.9 ± 0.7 | 2.4 ± 0.5 | 0.0003 |
| FEV1/FVC (%)¶ | 54.2 ± 12.4 | 74.3 ± 3.2 | <0.0001 |
| FEV1%predicted (%)¶ | 70.5 ± 21.6 | 88.1 ± 15.0 | 0.0002 |
| DLCO/VA (mmol/min/kPa/L)§ | 0.9 ± 0.4 | 1.1 ± 0.4 | N.S. |
| GOLD airflow limitation severity | |||
| 1/2/3/4 | 56/80/21/7 | - |
Notes: Data are presented as the mean ± standard deviation unless otherwise stated and were analyzed by Wilcoxon’s rank-sum test. †inhalation biomass; ¶n = 163; §n = 158.
Abbreviations: BMI, body mass index; CAT, COPD assessment test; COPD, chronic obstructive lung disease; DLCO/VA, carbon monoxide diffusing capacity of the lung for carbon monoxide and alveolar volume ratio; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; GOLD, Global Initiative for Chronic Obstructive Lung Disease; mMRC, modified Medical Research Council dyspnea scale; N.S., not significant (p > 0.05); VC, vital capacity.