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. 2020 Jan 1;10(2):602–614. doi: 10.7150/thno.36220

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Knockout of mdig enriches H3K9me3, H3K27me3, and/or reduces H3K4me3 on the genes in cell growth and stemness. A. Representative histone methylation profiles and expression of the indicated stemness genes in WT and KO cells as determined by ChIP-seq and RNA-seq, respectively. B. Stem cell signature assay for the genes with an increased enrichment of H3K9me3 following mdig knockout as determined by StemChecker software. C. Transcription factor target analysis of the genes with an increased enrichment of H3K9me3 following mdig knockout as determined by StemChecker software.