Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jan 1;10(2):797–815. doi: 10.7150/thno.38483

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The author(s)

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.

PMC Copyright notice

14-3-3ζ is a transcription regulation factor for diverse gene expressions. (A) Similarity analysis of whole transcriptional changes after treatment with 14-3-3ζ siRNA or PTA at 20 μM. (B) Scatter-plots showing correlation with transcriptional changes after treatment with 14-3-3ζ siRNA or PTA at 20 μM. (C) Heat map of gene expression changes to core autophagy-lysosome pathway after treatment with PTA. (D) Similarity analysis of autophagy-lysosome pathway-related transcriptional changes after treatment with 14-3-3ζ siRNA or PTA at 20 μM. (E) IGV screenshots for ATP5AP1L, ATP6V1G1 and ATP6V1D loci. (F) Heat map of gene expression changes to core endoplasmic reticulum stress pathway after treatment with PTA. (G) Similarity analysis of endoplasmic reticulum stress pathway-related transcriptional changes after treatment with 14-3-3ζ siRNA or PTA at 20 μM. (H) IGV screenshots for CANX, STT3B and DANJA1 loci. (I) Conserved motifs of transcription factors YBX1, TIF1β, FoxO1 and E2F3 were shown by TomTom analysis. (J) Histone H3 interaction with transcription factors was promoted by PTA in HA-tagged histone H3-transfected HEK293T cells. (K) 14-3-3ζ knockdown did not affect histone H3 binding to transcription factors.