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. 2020 Jan 1;10(2):782–796. doi: 10.7150/thno.38684

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(A) JC-1 reagent was applied to test the health of the mitochondria. When the mitochondria worked normal, the JC-1 molecules aggregate and emit red fluorescence. Otherwise, if the mitochondria are damaged, JC-1 is released to the cytosol and the JC-1 monomer molecular emits green fluorescence. (B) Fluorescence intensity of the cytometry flow with PE (red emission) and FITC (green emission) filter in four groups (I: Control, II: UCNP + MC540, III: AuNR@UCNP, IV: AuNR@UCNP@NB) with the scale bar = 50 μm.