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(A) In vivo thermal imaging and (B) time-dependent temperature changes of mice after treated with saline and BSA-Ce6@IrO2/MnO2 under an 808 nm laser irradiation for 10 min. (C) Relative tumor volume curves of MDA-MB-231 tumor bearing nude mice as a function of time and treatment. (D) Photographs and (E) weights of the tumors excised after 15 days of treatment. ***P < 0.001, **P < 0.01.
