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H&E, TUNEL, antigen Ki-67 immunohistochemistry and HIF-1α staining of tumor slides from MDA-MB-231 tumor bearing mice. Scale bars: 50 μm. Data were collected on day 15 from mice treated with (1) saline, (2) 808 nm + 660 nm laser irradiation, (3) BSA-Ce6@IrO2/MnO2 + 808 nm laser, (4) BSA-Ce6@IrO2/MnO2 + 660 nm laser, and (5) BSA-Ce6@IrO2/MnO2 + 808 nm + 660 nm lasers, respectively.
