Figure 1.

Quantification and analysis of circulating fibrocytes in inflammatory bowel disease [IBD]. [A] Circulating fibrocytes were increased in various colorectal diseases when compared with healthy controls, including Crohn’s disease [CD], ulcerative colitis [UC], and colorectal cancer. Levels of circulating fibrocytes were elevated in patients with diverticular disease but this was not significant. [B] Circulating fibrocytes trend towards increasing in patients with CD as their age at the time of surgery increases. [C] Circulating fibrocytes are increased in patients with CD who smoke or with a history of smoking when compared with those who never smoked. Smoking has no effect on levels of circulating fibrocytes in UC patients. [D] There was a trend of increasing circulating fibrocytes as the age of diagnosis increased in patients with UC. [E] Levels of circulating fibrocytes are highest in patients with CD with a stricturing [B2] behaviour type. Text at base of bars indicates number of samples analysed [n].