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. 2019 Jun 26;14(1):118–129. doi: 10.1093/ecco-jcc/jjz117

Table 1.

Demographics of recruited patients with Crohn’s disease and ulcerative colitis.

Variable CD [n = 35] UC [n = 15] p-value
Gender 0.849 [overall chi 2 ]
 Male 13 [37%] 6 [40%] 0.849 [Z test]
 Female 22 [63%] 9 [60%] 0.849 [Z test]
Age at operation [years] 36.9 ± 2.27 37.8 ± 3.10 0.814 [t test]
Age at diagnosis [years] 29.7 ± 2.05 35.3 ± 3.99 0.228 [t test]
Disease duration [months] 91.1 ± 16.11 63.6 ± 22.19 0.779 [t test]
Family history 0.198 [overall chi 2 ]
 Yes 11 [31%] 3 [20%] 0.412 [Z test]
 No 17 [49%] 12 [80%] 0.039 [Z test]
 Data not available 7 [20%] 0 [0%] 0.061 [Z test]
Smoking status 0.779 [overall chi 2 ]
 Active/history 22 [63%] 10 [59%] 0.281 [Z test]
 Non-smoker 13 [37%] 7 [41%] 0.281 [Z test]
Operation type
 Ileocolic resection 20 [57%] N/A N/A
 Ileocolic resection + other 1 [3%] N/A N/A
 Ileocolic resection + defunction 1 [3%] N/A N/A
 Small bowel resection 2 [6%] N/A N/A
 Sigmoid colectomy 1 [3%] N/A N/A
 Panproctocolectomy 2 [6%] N/A N/A
 Washout 1 [3%] N/A N/A
 Adhesiolysis 1 [3%] N/A N/A
 Defunction 6 [16%] N/A N/A
 Total colectomy N/A 11 [69%] N/A
 Completion proctecomy N/A 5 [31%] N/A
Medications at time of surgery 28 [80%] 13 [77%] 0.925 [overall chi 2 ]
 Aminosalicylates 9 [26%] 7 [41%] 0.222 [chi2 test]
 Steroid 14 [40%] 6 [35%] 0.804 [chi2 test]
 Antibiotics 3 [9%] 4 [24%] 0.124 [chi2 test]
 Immunosuppressants 8 [29%] 3 [18%] 0.704 [chi2 test]
  Thiopurines 7 [20%] 3 [18%] 0.842 [z test]
  Methotrexate 1 [3%] 0 [0%] 0.484 [Z test]
 Biologics 16 [46%] 10 [59%] 0.308 [chi2 test]
  anti-TNF 15 [43%] 9 [53%] 0.497 [Z test]
  anti-α 4β 7 1 [3%] 1 [6%] 0.596 [Z test]
 None 6 [17%] 3 [18%] 0.412 [chi2 test]
 Data not available 1 [3%] 1 [6%] 0.412 [chi2 test]
Montreal Classification of disease
Age at diagnosis 0.591 [overall chi 2 ]
 A1 ≤16 years old 2 [6%] 0 [0%] 0.347 [Z test]
 A2 = 17–40 years old 24 [69%] 8 [53%] 0.303 [Z test]
 A3 >40 years old 8 [29%] 4 [27%] 0.772 [Z test]
 Data not available 1 [3%] 1 [7%] 0.529 [Z test]
Location
 L1 Terminal ileum 19 [54%] N/A N/A
 L2 Colonic 3 [9%] N/A N/A
 L3 Ileocolic 7 [20%] N/A N/A
 L4 Upper GI 4 [11%] N/A N/A
 L1 + L4 1 [3%] N/A N/A
 E1 proctitis N/A 1 [7%] N/A
 E2 left-sided colitis N/A 6 [40%] N/A
 E3 pan- N/A 8 [53%] N/A
 Data not available 1 [3%] N/A N/A
Disease behaviour
 B1 non-stricturing, non-penetrating 5 [14%] N/A N/A
 B2 stricturing 14 [40%] N/A N/A
 B3 penetrating 15 [43%] N/A N/A
 P perianal involvement 3 [9%] N/A N/A
 Data not available 1 [3%] N/A N/A

Data are presented as mean ± SE. Bold text indicates statistically significant results. Italicised and underlined text indicates results for overall statistical tests. Biologic medication consists of anti-tumour necrosis factor [TNF] [adalimumab, infliximab, certolizumab, or golimumab] or anti-α 4β 7 integrin [vedolimumab] agents.

CD, Crohn’s disease; UC,ulcerative colitis; GI, gastrointestinal; N/A, not available.