. 2019 Nov 18;8:e51179. doi: 10.7554/eLife.51179

Video 3. Coarse-grained molecular dynamics simulation showing the diffusion of lipids into and out of the peripheral F_o cavity (orange sphere, as described in Figure 6—figure supplement 2C) within the lipid bilayer over a period of 4 µs.

A sliced view of the membrane bilayer is initially shown for reference, but later removed to allow viewing of the binding and unbinding phospholipids. Cardiolipin is indicated with purple, phosphatidic acid with yellow, phophatidylethanolamine with red, phosphatidylcholine with cyan acyl chains respectively. Lipids considered to be bound in the beginning or end of the simulation are visualized, demonstrating that cardiolipin replaces other lipids in the cavity during the simulation.

Video 3. Coarse-grained molecular dynamics simulation showing the diffusion of lipids into and out of the peripheral Fo cavity (orange sphere, as described in Figure 6—figure supplement 2C) within the lipid bilayer over a period of 4 µs.

Video 3. Coarse-grained molecular dynamics simulation showing the diffusion of lipids into and out of the peripheral F_o cavity (orange sphere, as described in Figure 6—figure supplement 2C) within the lipid bilayer over a period of 4 µs.