Table 3.
Concentrations of cytokines (pg/ml) in Mc/Mph cell culture supernatants.
| Cytokine | Without activation | Activation + GM-CSF (ng/ml) |
||||
|---|---|---|---|---|---|---|
| 0.0 | 0.01 | 0.1 | 1.0 | 10.0 | ||
| TNF-α | 320.8 (74.2–421.6) |
1198.2 (745.1–1553.6) |
1284 (533.8–1638) |
1166 (496.3–1516) |
1282.2 (551.1–1599.8) |
1418.6* (1002.4–1849.9) |
| IL-1β | 5.7 (0–157.6) |
459.0 (265.8–507.6) |
300.6 (118.2–621.6) |
372.6 (183.6–683.4) |
369.0 (337.8–754.8) |
399 (288–757.8) |
| IL-6 | 124.0 (36.0–733.5) |
8339 (4734–14577) |
10881 (6328–13633) |
9336 (5711–13269) |
9192 (5103–13315) |
12216* (8921–17225) |
| IL-10 | 0.8 (0–31.6) |
118.98 (95.87–127.54) |
124.95 (86.25–161.03) |
139.2 (92.93–165.3) |
93.6 (78.75–140.1) |
89.85 (75.68–139.65) |
Notes: Data are presented as Median with the first and third quartiles (Q1-Q3); * p < 0.05 – as compared to LPS-activated Mc/Mph cells cultured in the absence of GM-CSF.