TABLE 1.
Fertility status of knockout mouse lines.
| Group |
 Mouse lines
|
Fertility status (female) | Fertility status (male) |
| 1 | PP1 (Ppp1cc) global knockout (Chakrabarti et al., 2007b) | Fertile | Infertile |
| PP1γ2 conditional (testis-specific) knockout (Sinha et al., 2013) | Fertile | Infertile | |
| PP1γ1 rescue (in Ppp1cc knockout background) (Dudiki et al., 2019) | Fertile | Sub-fertile | |
| 2 | GSK3α global knockout (Bhattacharjee et al., 2015) | Fertile | Infertile |
| GSK3α conditional (testis-specific) knockout (Bhattacharjee et al., 2018) | Fertile | Infertile | |
| 3 | GSK3β global knockout (Hoeflich et al., 2000) | Embryonically lethal | |
| GSK3β conditional (testis-specific) knockout (Bhattacharjee et al., 2018) | Fertile | Fertile | |
| 4 | PKACα2 (testis isoform specific) knockout (Nolan et al., 2004) | Fertile | Infertile |
| 5 | sAC (Adcy10) knockout (Hess et al., 2005; Xie et al., 2006) | Fertile | Infertile |
| 6 | PPP3R2 (sperm isoform specific) knockout (Miyata et al., 2015) | Fertile | Infertile |
| PPP3CC (sperm isoform specific) knockout (Miyata et al., 2015) | Fertile | Infertile | |