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. 2019 Dec 18;13:557. doi: 10.3389/fncel.2019.00557

Figure 2.

Figure 2

Dopamine activates Kv7/M current in NAc-projecting VTA DA neurons. (A) Kv7/M currents recorded from DA neurons of WT (i,ii) and Kv7.4−/− (iii,iv) mice. Shown are time-courses of M current amplitudes recorded using whole-cell patch-clamp from VTA slices (for details, see “Materials and Methods” section). Summarized data are presented in (B). Error bars represent SEM. ***p < 0.001, *p < 0.05; N.S., not significant. One-way repeated-measures ANOVA with Bonferroni test for WT mice, paired t-test for Kv7.4−/− mice. N = number of animals; n, number of recordings.