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. 2019 Dec 24;9:19733. doi: 10.1038/s41598-019-56303-3

Table 1.

Clinical information of patients with favourable (free from ES/TS) and unfavourable (others) outcomes.

ES/TS free N = 7 ES/TS residual N = 10 p-value
Sex (boys: girls) 6: 1 9: 1 n.s.
Types of epilepsy syndrome n.s.
   West syndrome 2 8
   Symptomatic generalised epilepsy 5 2
Aetiology n.s.
   Structural abnormality 5 6
   Genetic/chromosomal syndrome 2 1
   Unknown 0 3
Age at epilepsy onset [months, range (mean)] 4–166 (49) 1–13 (5) n.s.
Total number of AEDs before CC [range (mean)] 4–8 (6.6) 6–10 (7.3) n.s.
Frequency of ES/TS n.s.
   1–20/day 5 5
   >20/day 2 5
Age at CC [months, range (mean)] 45–237 (125) 17–106 (51) 0.042
Procedure of CC n.s.
   Total callosotomy 6 8
   Anterior 4/5 callostomy 1 2
Outcomes of Engel’s classification NA
   I 7
   II 2
   III 4
   IV 4
Follow-up periods [months, range (mean)] 8–36 (17) 10–72 (26) n.s.

ES, epileptic spasms; TS, tonic spasms; AEDs: antiepileptic drugs; CC, corpus callosotomy; n.s., not significant; NA, not applicable. We used Fisher’s exact probability test, Welch t-test and chi-square test, appropriately. Tuberous sclerosis complex was classified to structural abnormality in aetiology.