Table 1.
ES/TS free N = 7 | ES/TS residual N = 10 | p-value | |
---|---|---|---|
Sex (boys: girls) | 6: 1 | 9: 1 | n.s. |
Types of epilepsy syndrome | n.s. | ||
West syndrome | 2 | 8 | |
Symptomatic generalised epilepsy | 5 | 2 | |
Aetiology | n.s. | ||
Structural abnormality | 5 | 6 | |
Genetic/chromosomal syndrome | 2 | 1 | |
Unknown | 0 | 3 | |
Age at epilepsy onset [months, range (mean)] | 4–166 (49) | 1–13 (5) | n.s. |
Total number of AEDs before CC [range (mean)] | 4–8 (6.6) | 6–10 (7.3) | n.s. |
Frequency of ES/TS | n.s. | ||
1–20/day | 5 | 5 | |
>20/day | 2 | 5 | |
Age at CC [months, range (mean)] | 45–237 (125) | 17–106 (51) | 0.042 |
Procedure of CC | n.s. | ||
Total callosotomy | 6 | 8 | |
Anterior 4/5 callostomy | 1 | 2 | |
Outcomes of Engel’s classification | NA | ||
I | 7 | — | |
II | — | 2 | |
III | — | 4 | |
IV | — | 4 | |
Follow-up periods [months, range (mean)] | 8–36 (17) | 10–72 (26) | n.s. |
ES, epileptic spasms; TS, tonic spasms; AEDs: antiepileptic drugs; CC, corpus callosotomy; n.s., not significant; NA, not applicable. We used Fisher’s exact probability test, Welch t-test and chi-square test, appropriately. Tuberous sclerosis complex was classified to structural abnormality in aetiology.