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. 2019 Dec 24;9:19746. doi: 10.1038/s41598-019-56327-9

Figure 6.

Figure 6

MicroRNA-548 cluster can attenuate lipopolysaccharide (LPS)-induced inflammation in hAECs. (A) HMGB1 mRNA and protein expression in miRNA-548 mimic and control mimic transfected hAECs that were not treated or treated with LPS. (B) HMGB1 levels in culture medium of miRNA-548 mimic and control mimic transfected hAECs that were not treated or treated with LPS. (C) IL-1β, IL-6, and IL-8 levels in culture medium of miRNA-548 mimic and control mimic transfected hAECs that were not treated or treated with LPS. **Significant difference (P < 0.001) compared with control mimic group, *Significant difference (P < 0.001) compared with control group. hAECs, human amniotic epithelial cells; LPS, Lipopolysaccharide; IL, interleukin.