RNA was collected from constructs after 1 d and 7 d, purified, and expression determined using real time RT-PCR. Expression of collagen I α1 chain (COL1A1, A), fibronectin (FN1, B), laminin β1 chain (LAMB1, C), and collagen IV α1 chain (COL4A1, D) was measured. Expression levels were normalized to glyceraldehyde 3-phosphate dehydrogenase (GAPDH) in each sample and then to expression in 27 mg/mL PEGVS at 1 d (ΔΔCt method). *: p < 0.05, relative to 40 mg/mL PEGVS same day, N=3.