Decreased diversity of MPO435–454 specific T cells (Tet+) relative to tetramer negative CD25−, CD25intermediate, and regulatory T cells. Matched bootstrapped diversity including species richness, Shannon entropy, and d50 diversity indices derived from T cell receptor beta (TRB) profiling are shown (n=5 patients, n=4 for tetramer positive and Treg samples) corrected for false discovery rate (FDR). * p<0.05