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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: J Autoimmun. 2019 Aug 2;106:102306. doi: 10.1016/j.jaut.2019.102306

Table 1.

In silico binding predictions using the Immune Epitope Database. Predicted percentile rank reports affinity of peptide compared to other randomly selected peptides with a lower percentile rank correlating to higher affinity.

Protein Peptide Predicted Percentile Rank Associated HLA Allele
Mouse MPO MPO413–427
(GEKLYQEARKIVGAM)		 12.19 HLA-DRB5*01:01
Human MPO MPO447–461
(RKIVGAMVQIITYRD)		 2.83 HLA-DRB4*01:01
Human MPO MPO105–119
(PVAATRTAVRAADYL)		 10.88 HLA-DQA1*05:01/
DQB1*02:01
Human MPO MPO488–502
(PRIANVFTNAFRYGH)		 7.82 HLA-DRB5*01:01
Human MPO MPO245–259
(DQERSLMFMQWGQLL)		 1.84 HLA-DPA1 *01:03/ DPB1*04:02
Human MPO MPO545–559
(PILRGLMATPAKLNR)		 2.48 HLA-DRB 1*04:04
Human MPO MPO409–423
(MPELTSMHTLLLREH)		 3.05 HLA-DPA1*01:01/
DPB1*04:01