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. 2020 Jan 1;11(1):213–228. doi: 10.7150/jca.35821

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STK24 silencing in M12 cell clones enhances tumor growth in vivo. The macroscopic appearance of the tumor masses (A) and spleen (B) after the orthotopic injection of either the pEGFP-control (EGFP-Ctrl) or the sgSTK24-expressing cell clones of tumor-bearing C57BL/6 mice on Day 16 are shown. The stomach weights (C) and spleen weights (D) of the EGFP-Ctrl, sgSTK24-1.2 and sgSTK24-2.1 tumor-bearing C57BL/6 mice on Day 16 are shown. The macroscopic appearances of the tumor masses (E) and the stomach weights (F) of EGFP-Ctrl, sgSTK24-1.2 and sgSTK24-2.1 tumor-bearing NOD/SCID mice on Day 16 are shown. *P < 0.01; **P < 0.001; ***P < 0.0001. The results are expressed as the mean stomach weight and the mean spleen weight, and the data are averaged from two independent experiments.