Table 2.
Univariate and multivariate analysis for predictors of OS in 90 HCC patients
| Variables | OS | |||
|---|---|---|---|---|
| Univariate | Multivariate | |||
| P-value | HR | 95%CI | P-value | |
| Gender (Female vs Male) | 0.234 | - | - | - |
| Age/year (≤ 50 ys vs > 50 ys) | 0.180 | - | - | - |
| HBsAg (Negative vs Positive) | 0.932 | - | - | - |
| AFP (ng/mL) (≤ 400 vs > 400) | 0.000** | 2.641 | 1.387-5.025 | 0.003** |
| Number of tumors (Single vs Multiple) | 0.022* | 2.174 | 1.036-4.560 | 0.040* |
| Tumor size d/cm (≤ 5 vs > 5) | 0.005** | 1.635 | 1.137-2.351 | 0.008** |
| Pathological grade (Ⅰ vs Ⅱ vs Ⅲ-Ⅳ) | 0.015* | 1.752 | 1.044-2.942 | 0.034* |
| PVTT (Present vs Absent) | 0.000** | 2.805 | 1.503-5.236 | 0.001** |
| TNM (Ⅰ vs Ⅱ vs Ⅲ-Ⅳ) | 0.000** | 2.566 | 1.721-3.826 | 0.000** |
| GSTA1 (Low vs Moderate vs High) | 0.036* | 2.675 | 1.853-4.192 | 0.047* |
*P<0.05, **P<0.01.
Abbreviations: OS: overall survival. HR: hazard radio. CI: confidence interval. HBsAg: hepatitis B surface antigen. AFP: alpha-fetoprotein. PVTT: portal vein tumor thrombosis. TNM: tumor-node-metastasis. GSTA1: Glutathione S-transferase α1.