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. 2020 Jan 1;11(2):334–344. doi: 10.7150/jca.32989

Figure 4.

Figure 4

SFI synergizes with Gefitinib to induce apoptosis. (A, B and C) Apoptosis assay was conducted with SFI (1:10) and Gefitinib 4 μM alone or in combination for 24 h by Flow cytometry. **p<0.01 or ***p<0.001 compared to control group. (D, E and F) Western blotting was used to detect cleaved-caspase 3, cleaved-caspase 9, bax, and Bcl-2 protein expression after being treated with SFI (1:10) and Gefitinib 4 μM alone or in combination for 24 h. #p<0.05, ##p<0.01 or ###p<0.001 compared to control group. *p<0.05, **p<0.01 or ***p<0.001 compared to combination group.