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. 2020 Jan 1;11(2):460–467. doi: 10.7150/jca.34773

Fig 1.

Fig 1

Genipin enhances oxaliplatin-induced cell death in gastric cancer cell lines. (A) Treatment with 0-100 µM oxaliplatin for 24 h in gastric cancer cell lines and HFE-145. (B) Molecular structure of genipin. (C) Cell proliferation of gastric cancer cell lines was measured by using the MTT assay after treatment with 0-300 µM genipin for 24h (D) Cell survival of gastric epithelial cell line HFE-145 was measured using trypan blue staining. (E) Combination index for combination of genipin and oxaliplatin, CI = 0.1-0.3, Strong Synergism; CI= 0.3-0.7, Synergism. (F) Cell survival of gastric cancer cells were measured using trypan blue staining. The data are expressed as the mean of three independent experiments. ***P < 0.001, *P < 0.05, ns : not significant.