Table 1.
IC50 ± SD (µM) a [Resistance folds] b | |||||
---|---|---|---|---|---|
SW620 | SW620/Ad300 | KB-3-1 | KB-C2 | HEK293/pcDNA3.1 | HEK293/ABCB1 |
6.848 ± 0.338 | 7.094 ± 0.569 [1.0] |
14.315 ± 1.676 | 9.68 ± 0.085 [0.8] |
6.65 ± 0.552 | 7.57 ± 0.339 [1.1] |
The cytotoxicity of tetrandrine in several pairs of parental and drug resistant cancer cell lines. a IC50 represent mean ± SD of three independent experiments performed in triplicate. b Resistance folds (values in square brackets) were calculated by dividing the IC50 values of resistant cells by the IC50 of parental cells.