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. 2019 Nov 30;24(23):4383. doi: 10.3390/molecules24234383

Table 1.

Cytotoxicity of tetrandrine in parental and drug resistant cancer cells (Mean ± SD).

IC50 ± SD (µM) a [Resistance folds] b
SW620 SW620/Ad300 KB-3-1 KB-C2 HEK293/pcDNA3.1 HEK293/ABCB1
6.848 ± 0.338 7.094 ± 0.569
[1.0]
14.315 ± 1.676 9.68 ± 0.085
[0.8]
6.65 ± 0.552 7.57 ± 0.339
[1.1]

The cytotoxicity of tetrandrine in several pairs of parental and drug resistant cancer cell lines. a IC50 represent mean ± SD of three independent experiments performed in triplicate. b Resistance folds (values in square brackets) were calculated by dividing the IC50 values of resistant cells by the IC50 of parental cells.