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. 2019 Nov 20;24(23):4218. doi: 10.3390/molecules24234218

Figure 3.

Figure 3

Effects of SMe1EC2M3 and WAY100135 on the excitability of 5-HT neurons of the DRN. (A): representative recording from a single neuron; (B): summary effect from seven neurons from seven rats, expressed as % ± SEM of basal activity. SMe1EC2M3 was applied at the cumulative doses of 0.25–1.5 mg/kg (i.v.). Two minutes after the last SMe1EC2M3 administration, a selective antagonist of 5-HT1A receptors, WAY100135, was injected (0.1 mg/kg, i.v.); *p < 0.05, one-way ANOVA for repeated measures; #p < 0.05, Fisher´s LSD post-hoc test.