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. 2019 Dec 3;24(23):4420. doi: 10.3390/molecules24234420

Table 3.

Comparison of the total phenol content (TPC), total flavonoid content (TFC) and total proanthocyanidin oligomer content (OPC) contents between commercially available standardized extracts (as given by the supplier) and infusions at 10 min extraction time (as determined in this work). Q = quercetin, CY = cyanidin, GA = gallic acid, HY = hyperoside, epiCAT = epicatechin. a as for 2017.

Standardized Extracts Uptake Quantity Dry Extract Content Dry Plant: Dry Extract Ratio Plant Organ Excipients Extraction Solvent TPC TFC OPC Price
(€)
Treatment Cost/Day
(cents)
Cost/30 Days (€) a
EPS Phyto-prevent® 5–10 mL 900 mg/5 mL - Leaves & flowers Glycerol - - 7.5–12.5 mg eq. Q/5 mL (0.8–1.4 %) - 19.89/150 mL 66.3/5 mL 19.9
WS1442® crataegutt novo 450 (or Cardiplant® 450 or Cardio Max WS 1442®) 1–2 tablets 450 mg/1 tablet 4.0–6.6:1 Leaves & flowers Glucose, SiO2, Fe2O3, TiO2, sucrose, gelatine, macrogol, citric acid, … EtOH (45 %) - - 78–90.6 mg eq. epiCAT/1 tablet (17.3–20.1 %) 16.13/50 tablets 64.5/2 tablets 19.4
Crataegisan ® Bioforce 30–90 drops (0.75−2.25 mL) 690 mg/90 drops 3.2:1 Fruits EtOH (46−54%) EtOH (50 %) 12.7 mg eq. GA/90 drops (1.84 %) - 6.4 mg/90 drops (0.93%) 10.50/50 mL 52.5/90 drops 15.8
Faros 300® LI 132 3 Tablets 300 mg/1 tablet 4.0–7.0:1 Leaves, flowers & fruits Glucose, SiO2, lactose, TiO2, sucrose, gelatine, macrogol, … MeOH (70 %) - 6.6 mg eq. HY/1 tablet (2.2 %) - 23.25/100 tablets 69.7/3 tablets 20.9
Infusion
(lot no. 20335)
1–2 infusions 555 mg/10 min infusion
(from 2.5 g ground dry plant)
4.3–4.6:1 Leaves & flowers Water Water 82 mg eq. GA/1 infusion 8.6 mg eq. Q/1 infusion 9.8 mg eq. CY/1 infusion 29.25/1 kg 7.3/1 infusion 2.2