Table 5.
Anti-microbial activities of alkaloids isolated from Annona genus.
| Compound | MIC (µg/mL) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| KZ | SA | Sap | SE | Sep | EF | EC | PA | CA | CP | CD | CDb | Fm | |
| A. salzmannii [89] | - | ||||||||||||
| Liriodenine 11 | - | >500 | >500 | 50 | 50 | - | - | - | - | - | 50 | 100 | - |
| Anonaine 8 | 50 | >500 | 50 | 25 | 50 | - | - | - | - | - | 50 | 50 | - |
| Asimilobine 9 | 50 | >500 | 50 | 50 | 50 | 100 | - | - | >500 | >500 | >500 | 50 | - |
| Reticuline 19 | 250 | >500 | >500 | 100 | 100 | 250 | - | - | 100 | 100 | >500 | >500 | - |
| Annona squamosal [90] | |||||||||||||
| (−)-(R)-anonaine 8 [90] | - | - | - | - | - | - | - | - | - | - | - | - | 30–39 * |
| Cleistopholine 1 | - | - | - | 250 | 250 | 250 | - | - | - | - | - | 250 | - |
| Chloramphenicol | 50 | 25 | 25 | 50 | 50 | 50 | 50 | 850 | 12.5 | 12.5 | 12.5 | 12.5 | - |
-: no data available; KZ: Kocuriarhizophila (ATCC 9341); SA: Staphylococcus aureus (ATCC14458); SAp:S. aureuspenicilinase-(8-); SE: Staphylococcus epidermidis (ATCC 12228); Sep; S. epidermidis (6ep); EF: Enterococcus faecalis (Ef); EC: Escherichia coli (ATCC 10538); PA: Pseudomonas aeruginosa (ATCC 27853)c; CA: Candida albicans (ATCC 10231); CA: Candida albicans(ATCC 10231); CP: Candida parapsilosis (ATCC 22019); CD: Candida dubliniensis (ATCC 777); CDb Candida dubliniensis (ATCC 778157); FM: Fusarium moniliforme. * inhibition diameter in mm.