Skip to main content
. 2019 Nov 26;24(23):4318. doi: 10.3390/molecules24234318

Table 4.

Physiochemical properties of CPP-CPG2 N-terminal conjugates.

Peptide Number Name of the Conjugate Number of Amino Acids Mw (Da) pI Instability Index Aliphatic Index GRAVY
1 Transportan 10 (TP10)-CPG2 414 43860.19 8.37 23.99 97.20 −0.116
2 Ala43 substitution mutant of pAntp (43-58)-CPG2 409 43839.07 8.82 25.71 91.69 −0.218
3 Crot (27–39) derevative 1-CPG2 403 42996.11 8.48 24.58 90.87 −0.187
4 Crot (27–39) derevative 2-CPG2 403 43035.15 8.48 26.37 90.87 −0.196
5 Crot (27–39) derevative 3-CPG2 403 43035.15 8.48 26.00 90.87 −0.196
6 CyLoP-1-CPG2 403 43074.18 8.48 27.79 90.87 −0.205
7 Crot (27–39) derevative 4-CPG2 404 43131.24 8.48 27.75 90.64 −0.206
8 Crot (27–39) derevative 5-CPG2 404 43189.27 8.21 27.75 90.64 −0.214
9 pAntp (49–58)-CPG2 403 43099.16 8.65 26.37 90.87 −0.228
10 Tat (48–60)-CPG2 406 43396.46 9.08 31.77 90.20 −0.279
11 pAntp (45–58)-CPG2 407 43639.86 8.82 25.79 91.89 −0.215
12 Bip15–CPG2 398 42278.25 6.56 24.66 93.97 −0.159
13 pAntp (47–58)-CPG2 405 43398.53 8.65 26.29 91.38 −0.218
14 II-CPG2 411 43554.90 8.64 23.83 97.20 −0.121
15 Crot (27–39) derevative 6-CPG2 403 43074.18 8.48 26.37 90.87 −0.205
16 Crot (27–39) derevative 7-CPG2 407 43419.60 8.61 27.62 89.98 −0.209
17 Crot (27–39) derevative 8-CPG2 404 43202.36 8.66 27.75 90.64 −0.215
18 Crot (27–39) derevative 9-CPG2 405 43317.45 8.47 27.70 90.42 −0.223
19 pAntp (46–58)-CPG2 406 43526.70 8.82 26.04 91.16 −0.227
20 7-CPG2 408 43701.80 8.39 28.82 90.71 −0.215
21 No.14–2-CPG2 408 43652.73 8.38 27.74 90.96 −0.208
22 No.14-CPG2 408 43678.77 8.38 28.82 90.71 −0.216
23 No.14–7-CPG2 408 43763.88 8.38 28.38 90.71 −0.216
24 Crot (27–39)-CPG2 406 43448.64 8.47 28.46 90.20 −0.217
25 Crot (27–39) derevative 10-CPG2 405 43345.50 8.53 28.51 90.42 −0.224
26 Crot (27–39) derevative 11-CPG2 406 43432.58 8.53 28.46 90.20 −0.226
27 Crot (27–39) derevative 12-CPG2 406 43432.58 8.53 29.27 90.20 −0.226
28 pVEC mutant 1-CPG2 411 43802.04 8.66 25.76 95.52 −0.169
29 pVEC mutant 2-CPG2 411 43802.04 8.66 27.15 95.52 −0.169
30 pVEC mutant 3-CPG2 411 43830.05 8.67 27.97 95.52 −0.171
31 Crot (27–39) derevative 13-CPG2 405 43320.46 8.17 27.70 90.42 −0.208
32 ARF(1–22)-CPG2 415 44329.74 8.93 28.88 94.10 −0.158
33 M918-CPG2 415 44329.74 8.93 28.88 94.10 −0.158
34 pAntp (51–58)-CPG2 401 42823.85 8.65 26.45 91.32 −0.227
35 pAntp (44–58)-CPG2 408 43767.99 8.82 25.75 91.67 −0.223
36 pAntp (50–58)-CPG2 402 42951.98 8.65 26.41 91.09 −0.235
37 Ala44 substitution mutant of pAntp (43–58)-CPG2 409 43867.13 8.95 25.71 91.69 −0.221
38 PDX -1-PTD-CPG2 409 43933.19 8.95 27.26 91.44 −0.233
39 No.14–25-CPG2 408 43628.71 8.39 27.26 90.71 −0.199
40 No.14–17-CPG2 408 43614.68 8.40 28.66 90.96 −0.210
41 No.14–18-CPG2 408 43690.78 8.39 29.00 90.96 −0.211
42 No.14–20-CPG2 408 43676.75 8.39 29.50 90.96 −0.211
43 No.14–21-CPG2 408 43676.75 8.39 29.02 90.96 −0.211
44 No.14–35-CPG2 408 43720.81 8.39 30.02 90.96 −0.212
45 No.14–1-CPG2 408 43706.78 8.39 29.02 90.71 −0.217
46 30-CPG2 408 43660.71 8.37 27.65 90.71 −0.219
47 Ala45 substitution mutant of pAntp (43–58)-CPG2 409 43882.10 8.95 26.39 90.73 −0.240
48 Ala46 substitution mutant of pAntp (43–58)-CPG2 409 43867.09 8.83 26.60 91.69 −0.220
49 Ala47 substitution mutant of pAntp (43–58)-CPG2 409 43882.10 8.95 26.39 90.73 −0.240
50 Ala48 substitution mutant of pAntp (43–58)-CPG2 409 43809.00 8.95 26.19 91.69 −0.227
51 Ala49 substitution mutant of pAntp (43–58)-CPG2 409 43848.08 8.95 25.82 91.69 −0.236
52 Ala50 substitution mutant of pAntp (43–58)-CPG2 409 43867.13 8.95 26.19 91.69 −0.221
53 pAntpHD (Pro50)-CPG2 409 43893.17 8.95 26.66 91.44 −0.229
54 Ala51 substitution mutant of pAntp (43–58)-CPG2 409 43881.16 8.95 26.19 91.69 −0.221
55 Ala52 substitution mutant of pAntp (43–58)-CPG2 409 43839.07 8.82 24.78 91.69 −0.218
56 Met-Arg-CPG2 409 43924.18 8.95 26.00 91.44 −0.233
57 Ala54 substitution mutant of pAntp (43–58)-CPG2 409 43864.07 8.95 26.19 91.69 −0.234
58 Penetratin-CPG2 409 43924.18 8.95 26.19 91.44 −0.233
59 Retro - Tat (57–49)-CPG2 402 43017.05 9.08 30.55 91.09 −0.264
60 R6-CPG2 399 42632.57 8.86 32.28 91.78 −0.238
61 R9-CPG2 402 43101.13 9.19 36.38 91.09 −0.269
62 Crot (27–39) derevative 14-CPG2 402 42971.04 8.53 27.84 91.09 −0.212
63 Crot (27–39) derevative 15-CPG2 403 43058.12 8.52 28.27 90.87 −0.214
64 Rev (34–50)-CPG2 410 44115.2 9.18 32.92 89.56 −0.309
65 HIV-1 Rev (34–50)-CPG2 412 44275.39 9.13 32.60 89.13 −0.302
66 Bip6-CPG2 398 42204.11 6.55 25.89 93.97 −0.160
67 Bip1-CPG2 398 42264.22 6.55 25.22 93.72 −0.159
68 Bip2-CPG2 398 42234.13 6.55 25.41 93.72 −0.166
69 Bip16-CPG2 398 42234.09 6.22 26.44 93.72 −0.165
70 pAntp (48–58)-CPG2 404 43285.37 8.65 26.33 90.64 −0.229
CPG2 393 41695.44 6.22 25.33 93.18 −0.173