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. 2019 Nov 22;24(23):4253. doi: 10.3390/molecules24234253

Figure 7.

Figure 7

The effects of chronic administration of BSO and GBR 12909, alone or in combination, during the early postnatal life on cognitive functions assessed in adult 91-day-old rats in the novel object recognition test (NOR) test. (A) Effects of the examined model compounds on exploration of two identical objects in the acquisition trial (session T1). (B) Effects of the examined model compounds on exploration of a novel and a familiar object in the retention trial (session T2). (C) Effects of the examined model compounds on the recognition index. Data are presented as the mean ± SEM, n = 10 for each group. Letters indicate statistically significant differences between the exploration time of a familiar and a novel object in the session T2 within each studied group, according to the Student’s t-test for independent samples, aaap < 0.001 vs. object A. Statistical analysis of recognition index was performed using a two-way ANOVA; symbols indicate significance of differences according to the Newman–Keuls post-hoc test, ***p < 0.001, vs. control; ###p < 0.001 vs. BSO-; and ∆∆∆p < 0.001 vs. GBR 12909-treated groups.