Table 1.
Compound | IC50 (µM) | ORAC-FL Index | Ep (mV) | |||||
---|---|---|---|---|---|---|---|---|
R1 | R2 | R3 | DPPH• | ABTS•+ | GO• | |||
2 (TFA) | 47.8 ± 0.9a | 19.9 ± 1.0a | 4.25 ± 0.10a | 0.34 ± 0.04a | 271 | |||
3 | 49.8 ± 0.7 | 20.6 ± 0.7 | 4.50 ± 0.08 | 0.12 ± 0.02 | 198 | |||
4 | 47.3 ± 0.7 | 19.9 ± 0.3 | 4.41 ± 0.15 | 0.15 ± 0.01 | 186 | |||
5 | 42.7 ± 2.1 | 22.9 ± 0.6 | 6.70 ± 0.07 | 0.30 ± 0.03 | 218 | |||
6 | 50.7 ± 1.6 | 27.0 ± 1.8 | 6.66 ± 0.13 | 0.34 ± 0.01 | 245 | |||
1(FA) | 64.6 ± 1.9a | 16.8 ± 0.4a | 37.5 ± 2.5a | 3.2 ± 0.1a | 344 b | |||
7 | 61.7 ± 0.8 | 25.6 ± 1.8 | 76.4 ± 3.6 | 4.0 ± 0.4 | 327 | |||
8 | 61.2 ± 0.7 | 26.0 ± 1.7 | 70.7 ± 2.5 | 3.7 ± 0.3 | 338 | |||
9 | 43.9 ± 1.6 | 16.6 ± 0.3 | 3.90 ± 0.1 | 3.2 ± 0.3 | 291 | |||
10 | 69.7 ± 3.8 | 19.8 ± 0.8 | 31.2 ± 3.9 | 2.7 ± 0.1 | 351 | |||
Trolox | ---- | ---- | ---- | 24.6 ± 0.9 | 18.2 ± 0.5 | 2.98 ± 0.15 | 1.00 ± 0.02 | 110 |