Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Dec 3;24(23):4415. doi: 10.3390/molecules24234415

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Cytokine expression of THP M0 macrophages after 72 h treatment with 7-epi-clusianone (A) TNFα and (B) IL-6 by rt-PCR. Gene expression was normalized to the housekeeping gene GAPDH and the control group, non-treated THP-1 M0 macrophages (2^−ΔΔC). M1 macrophages were stimulated with LPS and IFN for 24 h and were characterized by rt-PCR to verify phenotypic markers (TNFα and IL-6). Cytokine concentration in culture media was determined for (C) TNFα and (D) IL-6 by ELISA assay. p values of less than 0.05 were significant. (* denotes significant difference compared to the control group and & denotates significant difference compared to the positive control (M1 macrophages)).