Table 1.
Demographic, laboratory, and angiographic characteristics of study population.
| Characteristics | All patients (n=711) | STEMI (n=405) | NSTEMI (n=306) | p |
|---|---|---|---|---|
| Age, year | 71.99±0.19 | 71.73±0.25 | 72.32±0.30 | 0.13 |
| Sex (Male), n (%) | 476 (66.95) | 272 (67.16) | 204 (66.67) | 0.89 |
| Smoking, n (%) | 210 (29.54) | 130 (32.10) | 80 (26.14) | 0.09 |
| Drinking, n (%) | 150 (21.10) | 86 (21.23) | 64 (20.92) | 0.94 |
| Hypertension, n (%) | 423 (59.49) | 237 (58.52) | 186 (60.78) | 0.54 |
| Prior CAD, n (%) | 78 (10.97) | 42 (10.37) | 36 (11.76) | 0.56 |
| Diabetes, n (%) | 179 (25.18) | 97 (23.95) | 82 (26.80) | 0.39 |
| Stroke, n (%) | 96 (13.50) | 53 (13.09) | 43 (14.05) | 0.71 |
| SBP on admission (mmHg) | 129.72±0.93 | 127.95±1.28 | 132.06±1.33 | 0.03 |
| DBP on admission (mmHg) | 75.62±0.55 | 75.82±0.77 | 75.36±0.75 | 0.67 |
| HR on admission (beats/min) | 77.11±0.60 | 78.94±0.75 | 74.69±0.86 | <0.01 |
| hospitalization day | 8.69±0.26 | 8.40±0.28 | 9.07±0.47 | 0.20 |
| Killip class, III–IV, n (%) | 101 (14.21) | 63 (15.56) | 38 (12.42) | 0.24 |
| LVEF, % | 53.04±0.46 | 50.93±0.47 | 55.82±0.68 | <0.01 |
| Creatinine (μmol/L) | 91.93±0.33 | 93.96±1.84 | 89.24±1.96 | 0.08 |
| AST (u/L) | 91.27±4.07 | 123.77±6.15 | 77.05±4.41 | <0.01 |
| ALT (u/L) | 35.83±1.45 | 38.19±1.91 | 32.71±2.22 | 0.06 |
| NT-proBNP, pg/mL | 4635.84±292.81 | 4823.00±367.95 | 4388.14±475.45 | 0.46 |
| CTnI, pg/mL | 15015.62±699.78 | 18398.24±1001.14 | 10538.61±881.01 | <0.01 |
| HDL, mmol/L | 1.09±0.02 | 1.08±0.02 | 1.10±0.03 | 0.72 |
| LDL, mmol/L | 2.58±0.04 | 2.62±0.05 | 2.54±0.05 | 0.26 |
| Total triglyceride, mmol/L | 1.36±0.04 | 1.30±0.05 | 1.42±0.06 | 0.14 |
| Total cholesterol, mmol/L | 4.12±0.04 | 4.17±0.06 | 4.05±0.06 | 0.17 |
| WBC count (109/L) | 9.18±0.14 | 9.84±0.20 | 8.30±0.19 | <0.01 |
| Platelet count (109/L) | 202.78±2.53 | 206.37±3.43 | 198.03±3.71 | 0.10 |
| Neutrophil count (109/L) | 7.14±0.14 | 7.86±0.20 | 6.17±0.19 | <0.01 |
| Lymphocyte count (109/L) | 1.40±0.02 | 1.32±0.03 | 1.50±0.04 | <0.01 |
| Monocyte count (109/L) | 0.57±0.01 | 0.58±0.02 | 0.55±0.01 | 0.21 |
| Hemoglobin (mg/dL) | 127.03±0.71 | 126.94±0.92 | 127.15±1.10 | 0.88 |
| SII | 1392.69±56.85 | 1645.60±81.60 | 1057.95±71.86 | <0.01 |
| Medications in-hospital, n (%) | ||||
| Antiplatelet therapy | 666 (93.67) | 385 (95.06) | 281 (91.83) | 0.08 |
| Beta-blocker | 507 (71.31) | 281 (69.38) | 226 (73.86) | 0.19 |
| ACEI/ARB | 500 (70.32) | 276 (68.15) | 224 (73.20) | 0.14 |
| Statin | 694 (97.61) | 393 (97.04) | 301 (98.37) | 0.25 |
| Angiographic and procedural characteristics | ||||
| Culprit vessel, n (%) | ||||
| LAD | 622 (87.48) | 362 (89.38) | 260 (84.97) | 0.08 |
| LCX | 451 (63.43) | 243 (60.00) | 208 (67.97) | 0.03 |
| RCA | 458 (64.42) | 260 (64.20) | 198 (64.71) | 0.89 |
| No. of diseased vessels, n (%) | 0.56 | |||
| 0 | 1 (0.14) | 0 (0.00) | 1 (0.33) | |
| 1 | 196 (27.57) | 115 (28.40) | 81 (26.47) | |
| 2 | 208 (29.25) | 121 (29.88) | 87 (28.43) | |
| 3 | 306 (43.04) | 169 (41.73) | 137 (44.77) | |
| Onset to reperfusion time, h | 14.29±0.33 | 13.37±0.43 | 15.51±0.50 | <0.01 |
| Tirofiban use, n (%) | 591 (83.12) | 348 (85.93) | 243 (79.41) | 0.03 |
| Stent use, n (%) | 533 (74.96) | 318 (78.52) | 215 (70.26) | 0.01 |
| Use of thrombus aspiration, n (%) | 72 (10.13) | 60 (14.81) | 12 (3.92) | <0.01 |
| Stent diameter, mm | 2.27±0.06 | 2.40±0.08 | 2.08±0.08 | <0.01 |
| Stent length, mm | 20.45±0.51 | 21.84±0.69 | 18.60±0.74 | <0.01 |
| Preprocedural TIMI grade, n (%) | 0.01 | |||
| 0 | 439 (61.74) | 270 (66.67) | 169 (55.23) | |
| 1 | 245 (34.46) | 124 (30.62) | 121 (39.54) | |
| 2 | 24 (3.38) | 11 (2.72) | 13 (4.25) | |
| 3 | 3 (0.42) | 0 (0.00) | 3 (0.98) | |
| Postprocedural TIMI grade, n (%) | 0.11 | |||
| 0 | 90 (12.66) | 45 (11.11) | 45 (14.71) | |
| 1 | 40 (5.63) | 18 (4.44) | 22 (7.19) | |
| 2 | 28 (3.94) | 19 (4.69) | 9 (2.94) | |
| 3 | 553 (77.78) | 323 (79.75) | 230 (75.16) | |
| Gensini score | 93.76±1.99 | 94.59±2.39 | 92.67±3.36 | 0.64 |
Mean±SEM and n (%) are reported for continuous and categorical variables, respectively. SEM – standard error of the mean.
STEMI – ST-segment elevation myocardial infarction; NSTEMI – non-ST-elevation myocardial infarction; CAD – coronary artery disease; SBP – systolic blood pressure; DBP – diastolic blood pressure; HR – heart rate; LVEF – left ventricular ejection fraction; AST – aspartate aminotransferase; ALT – alanine aminotransferase; NT-proBNP – N-terminal pro-brain natriuretic peptide; CTnI – cardiac troponin I; HDL – high-density lipoprotein cholesterol; LDL – low-density lipoprotein cholesterol; WBC – white blood cell; SII – systemic immune-inflammatory index; ACEI/ARB – angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker; LAD – left coronary artery; LCX – left circumflex; RCA – right coronary artery; TIMI – thrombolysis in myocardial infarction.