Table 2.
Predictors of in-hospital mortality in univariate and multivariate Cox regression analysis.
| Variables | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p | HR | 95% CI | p | |
| Age | 1.03 | 0.98–1.09 | 0.24 | NS | ||
| Sex (Male) | 1.55 | 0.89–2.69 | 0.12 | NS | ||
| Gensini score | 1.01 | 1.00–1.01 | 0.01 | NS | ||
| Smoking | 1.55 | 0.85–2.83 | 0.16 | NS | ||
| Hypertension | 1.06 | 0.61–1.85 | 0.85 | NS | ||
| Prior CAD | 2.42 | 1.27–4.62 | 0.01 | 2.77 | 1.38–5.57 | <0.01 |
| Diabetes | 1.06 | 0.59–1.93 | 0.84 | NS | ||
| Killip class | 2.38 | 1.85–3.05 | <0.01 | 1.64 | 1.24–2.18 | <0.01 |
| LVEF | 0.95 | 0.93–0.97 | <0.01 | NS | ||
| CTnI | 2.50 | 1.37–4.57 | <0.01 | 2.62 | 1.31–5.23 | 0.01 |
| WBC | 1.13 | 1.07–1.19 | <0.01 | NS | ||
| Neutrophil counts | 1.15 | 1.09–1.21 | <0.01 | 1.12 | 1.04–1.21 | <0.01 |
| Lymphocyte counts | 0.82 | 0.53–1.28 | 0.38 | |||
| Platelet counts | 1.00 | 0.99–1.00 | 0.26 | |||
| Hemoglobin | 0.96 | 0.95–0.98 | <0.01 | 0.97 | 0.96–0.98 | <0.01 |
| Total cholesterol | 0.83 | 0.64–1.06 | 0.14 | |||
| Total triglyceride | 0.92 | 0.68–1.24 | 0.58 | |||
| LDL | 0.91 | 0.68–1.21 | 0.50 | |||
| HDL | 0.33 | 0.12–0.91 | 0.03 | NS | ||
| creatinine | 1.01 | 1.00–1.02 | <0.01 | 1.01 | 1.00–1.01 | 0.02 |
| SII | 2.95 | 1.27–6.87 | 0.01 | 3.32 | 1.55–7.10 | <0.01 |
HR – hazard ratio; CI – confidence interval; NS – no statistical significance; CAD – coronary artery disease; LVEF – left ventricular ejection fraction; CTnI – cardiac troponin I; WBC – white blood cell; HDL – high-density lipoprotein cholesterol; LDL – low-density lipoprotein cholesterol; SII – systemic immune-inflammation index. NS stands for the factors which have no statistically significance in multivariate analysis. Bolded differences show statistical difference at the p<0.05 for multivariate analysis.