Table 3.
Predictors of in-hospital major adverse cardiovascular and cerebrovascular events in univariate and multivariate Cox regression analysis.
| Variables | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p | HR | 95% CI | p | |
| Age | 1.00 | 0.98–1.03 | 0.85 | NS | ||
| Sex (Male) | 1.31 | 1.01–1.71 | 0.04 | NS | ||
| Gensini score | 1.00 | 0.99–1.00 | 0.57 | |||
| Smoking | 1.05 | 0.81–1.37 | 0.71 | NS | ||
| Hypertension | 1.11 | 0.86–1.45 | 0.42 | NS | ||
| Prior CAD | 1.14 | 0.78–1.67 | 0.51 | NS | ||
| Diabetes | 1.05 | 0.80–1.38 | 0.73 | NS | ||
| Killip class | 1.35 | 1.19–1.52 | <0.01 | 1.17 | 1.01–1.35 | 0.04 |
| LVEF | 0.98 | 0.97–0.99 | <0.01 | 0.98 | 0.97–0.99 | <0.01 |
| CTnI | 1.56 | 1.21–2.02 | <0.01 | 1.35 | 1.03–1.78 | 0.03 |
| WBC | 1.07 | 1.04–1.10 | <0.01 | NS | ||
| Neutrophil counts | 1.08 | 1.05–1.11 | <0.01 | 1.08 | 1.04–1.12 | <0.01 |
| Lymphocyte counts | 0.90 | 0.74–1.09 | 0.28 | |||
| Platelet counts | 1.00 | 0.99–1.00 | 0.31 | |||
| Hemoglobin | 0.99 | 0.99–1.00 | 0.02 | 0.99 | 0.99–1.00 | 0.02 |
| Total cholesterol | 0.98 | 0.88–1.09 | 0.72 | |||
| Total triglyceride | 0.99 | 0.87–1.12 | 0.84 | |||
| LDL | 0.99 | 0.87–1.12 | 0.83 | |||
| HDL | 1.13 | 0.83–1.54 | 0.44 | |||
| creatinine | 1.00 | 1.00–1.01 | 0.05 | NS | ||
| SII | 1.32 | 1.01–1.72 | 0.04 | 1.43 | 1.02–2.00 | 0.04 |
HR – hazard ratio; CI – confidence interval; NS – no statistical significance; CAD – coronary artery disease; LVEF – left ventricular ejection fraction; CTnI – cardiac troponin I; WBC – white blood cell; HDL – high-density lipoprotein cholesterol; LDL – low-density lipoprotein cholesterol; SII – systemic immune-inflammation index. NS stands for the factors which have no statistically significance in multivariate analysis. Bolded differences show statistical difference at the p<0.05 for multivariate analysis.