Table 5.
Predictors of long-term major adverse cardiovascular and cerebrovascular events in univariate and multivariate Cox regression analysis.
| Variables | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p | HR | 95% CI | p | |
| Age | 1.06 | 1.03–1.09 | <0.01 | 1.05 | 1.02–1.09 | <0.01 |
| Sex (male) | 1.36 | 0.98–1.88 | 0.06 | NS | ||
| Gensini score | 1.00 | 0.99–1.00 | 0.43 | |||
| Smoking | 1.04 | 0.75–1.44 | 0.83 | NS | ||
| Hypertension | 1.22 | 0.87–1.69 | 0.25 | NS | ||
| Prior CAD | 1.10 | 0.67–1.83 | 0.70 | NS | ||
| Diabetes | 1.27 | 0.89–1.83 | 0.19 | NS | ||
| Killip class | 1.91 | 1.60–2.27 | <0.01 | 1.57 | 1.29–1.90 | <0.01 |
| LVEF | 0.97 | 0.96–0.99 | <0.01 | 0.98 | 0.97–1.00 | 0.02 |
| CTnI | 1.50 | 1.09–2.08 | 0.01 | NS | ||
| WBC | 1.10 | 1.06–1.14 | <0.01 | NS | ||
| Neutrophil counts | 1.10 | 1.06–1.14 | <0.01 | NS | ||
| Lymphocyte counts | 0.66 | 0.50–0.88 | 0.01 | NS | ||
| Platelet counts | 1.00 | 0.99–1.00 | 0.80 | |||
| Hemoglobin | 0.99 | 0.98–1.00 | <0.01 | NS | ||
| Total cholesterol | 0.95 | 0.82–1.11 | 0.52 | |||
| Total triglyceride | 1.08 | 0.92–1.27 | 0.35 | |||
| LDL | 0.92 | 0.77–1.10 | 0.35 | |||
| HDL | 1.11 | 0.75–1.64 | 0.60 | |||
| creatinine | 1.01 | 1.00–1.01 | <0.01 | NS | ||
| SII | 2.22 | 1.61–3.07 | <0.01 | 1.72 | 1.23–2.40 | <0.01 |
HR – hazard ratio; CI – confidence interval; NS – no statistical significance; CAD – coronary artery disease; LVEF – left ventricular ejection fraction; CTnI – cardiac troponin I; WBC – white blood cell; HDL – high-density lipoprotein cholesterol; LDL – low-density lipoprotein cholesterol; SII – systemic immune-inflammation index. NS stands for the factors which have no statistically significance in multivariate analysis. Bolded differences show statistical difference at the p<0.05 for multivariate analysis.