Table 3.
PPARG allele frequencies in the 135 residents with unexplained mild visual impairment (UMVI) and 133 residents with normal vision (NV).
| SNP | Alleles | UMVI residents | NV residents | p value∗ | MAF | OR (95%CI) |
|---|---|---|---|---|---|---|
| number (%) | number (%) | |||||
| rs10865710 | G | 163 (60.4) | 14 (5.3) | 6.57E − 42 | 0.33 | 27.42 (15.18–49.51) |
| C | 107 (39.6) | 252 (94.7) | ||||
| rs1801282 | G | 22 (8.1) | 0 (0) | 1.99E − 06 | 0.04 | NA |
| C | 248 (91.9) | 266 (100) | ||||
| rs709158 | G | 95 (58.6) | 24 (21.4) | 1.00E − 09 | 0.43 | 5.20 (3.00–9.00) |
| A | 67 (41.4) | 88 (78.6) | ||||
| rs3856806 | T | 88 (32.6) | 21 (7.9) | 1.22E − 12 | 0.20 | 5.64 (3.38–9.42) |
| C | 182 (67.4) | 245 (92.1) |
MAF = minor allele frequency; OR = odds ratio; CI = confidence interval; NA, the odds ratio was not available where the number of individuals with two copies of the risk allele was zero. ∗χ2 test.