Table 4.
SNP | Genotype | UMVI residents | NV residents | HWpval | p value∗ | OR (95% CI)∗ | p value# | OR# (95% CI) |
---|---|---|---|---|---|---|---|---|
number | number | |||||||
rs10865710 | GG | 36 | 0 | 0.08 | 7.17E − 42 | NA | ||
GC | 91 | 14 | 6.40 (3.47–11.80) | 1.86E − 41 | 0.01 (0.00–0.02) | |||
CC | 8 | 119 | 0.07 (0.03–0.14) | (CC: GG + GC) | ||||
rs1801282 | GG | 0 | 0 | 1 | NA | NA | ||
GC | 22 | 0 | NA | 7.46E − 6 | 0.46 (0.40, 0.53) | |||
CC | 113 | 133 | 0.86 (0.61–1.21) | (CC: GG + GC) | ||||
rs709158 | GG | 25 | 4 | 0.33 | 3.35E − 09 | 4.43 (1.46–13.43) | 0.41 | 2.22 (0.67, 7.38) |
GA | 45 | 16 | 1.94 (1.00–3.78) | 6.9E − 7 | 20.46 (5.84, 71.61) | |||
AA | 11 | 36 | 0.21 (0.10–0.45) | 1.39E − 6 | 0.11 (0.04, 0.26) | |||
rs3856806 | TT | 16 | 0 | 0.10 | 1.24E − 10 | NA | ||
TC | 56 | 21 | 2.63 (1.51–4.58) | 8.92E − 10 | 0.16 (0.09–0.29) | |||
CC | 63 | 112 | 0.55 (0.37–0.82) | (CC: TT + TC) |
p value∗ (chi-square test); OR (95% CI) ∗(chi-square test); OR# (95 % CI); p value# (Bonferroni correction); OR' (Bonferroni correction); HWpval, Hardy–Weinberg equilibrium p value. OR = odds ratio; CI = confidence interval; NA, the odds ratio was not available where the number of individuals with two copies of the risk allele was zero. ∗χ2 test.