Table 2.
LncRNAs deregulated in lung cancer.
| LncRNA | Mechanism | Clinical utility | Expression | References |
|---|---|---|---|---|
| HOTAIR | Invasion; metastasis | Prognostic biomarker; therapeutic target | Upregulated | [28–30,67] |
| H19 | Proliferation; migration; invasion | Prognostic biomarker | Upregulated | [110–112] |
| MALAT1 | Migration; invasion; chemoresistance | Predictive biomarker | Upregulated | [24,113,114] |
| ANRIL | Proliferation; apoptosis; cell cycle | Prognostic biomarker | Upregulated | [115,116] |
| LINC00668 | Proliferation; migration; invasion; apoptosis. | Prognostic biomarker | Upregulated | [25,117] |
| LINC01436 | Metastasis | Prognostic biomarker | Upregulated | [31] |
| SUMO1P3 | Metastasis | Therapeutic target | Upregulated | [32] |
| MNX1-AS1 | Proliferation; migration; apoptosis | Prognostic biomarker | Upregulated | [21] |
| RHPN1-AS1 | Gefitinib resistance | Prognostic biomarker; therapeutic target | Downregulated | [118] |
| MIR31HG | Cell cycle; proliferation | Prognostic biomarker | Upregulated | [119] |