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HJSD increases the expression of CREB in rat hippocampal CA1 (a), CA3 (b), and DG (c) regions in vivo. Number of CREB-like immunoreactive cells in the hippocampal CA1 (d), CA3 (e), and DG (f) regions. Statistical significance was determined using one-way ANOVA; n = 3; ∗P < 0.05, ∗∗P < 0.01, ##P < 0.01, ∗Comparison with the epilepsy group; #Comparison with the control group. Positive expression of CREB (arrows) is indicated.
